Sedating side effects
In addition to the aforementioned precautions, patients should be interviewed to determine if they have any other condition that may lead to complications while undergoing treatment.Any head, neck, or spinal cord injuries should be noted as well as any diagnosis of osteoporosis.Sedation methods in dentistry include inhalation sedation (using nitrous oxide), oral sedation, and intravenous (IV) sedation.Inhalation sedation is also sometimes referred to as relative analgesia.However, paradoxical stimulation ranging from excitation through to tremors, hallucinations and convulsions may occur.Excessive doses in children have led to respiratory depression, coma and death.Prior to any oral sedation methods being used on a patient, screening must be done to identify possible health concerns.
The American Society of Anesthesiologists defines the continuum of sedation as follows: In the United Kingdom, deep sedation is considered to be a part of the spectrum of general anesthesia, as opposed to conscious sedation.
This reminder follows a report received by the Centre for Adverse Reactions Monitoring (CARM) concerning a three-year-old child who was given chlorphenamine for a lower respiratory tract infection and experienced a serious neurological disorder.
Fortunately, the child eventually recovered without any on-going ill-effects.
This drug has been reported to be unequivocally genotoxic and a presumed transspecies carcinogen, which implies a carcinogenic risk to humans.
Common (1% to 10%): Convulsion, dizziness, peripheral neuropathy, drowsiness Frequency not reported: Severe peripheral neuropathy has been reported in HIV-infected patients who received this drug in combination with antiretroviral drugs Common (1% to 10%): Hepatotoxicity, hepatic enzyme increased, cholestasis, hepatitis Frequency not reported: Both fatal and nonfatal hepatotoxicity have been reported in HIV-infected patients who received this drug in combination with antiretroviral agents1.
Pharmaceutical Society of Australia "APPGuide online.